Applies recent molecular discoveries to the evolving treatment of skin therapy and points out future research areas. Presenting the most up-to-date research in wound treatment, this comprehensive reference analyzes the critical alterations in the composition and organization of the extracellular matrix following injury. Beginning with a chemicobiological history of wound healing and leading into a study of artificial wound coverings, the book progresses toward the application of fetal wound materials for adult scarless repair and the role of different macromolecules in wound repair. With nearly 40 recognized specialists addressing the most recent developments in wound care today, Scarless Wound Healing investigates the multifaceted role of hyaluronan in epithelial recovery the effects of changes in sulfation on skin proteoglycans distribution and composition changes of proteoglycans, including syndecans in scarring the role of the hyaluronan receptors RHAMM and CD44 in wound recovery the biology of fibroproliferative disorders the influence of transforming growth factors (TGF) to stimulate cell recovery fetal wound healing and more! Supplemented with over 1500 literature references, drawings, and tables, Scarless Wound Healing is invaluable reading for all plastic, reconstructive, cosmetic, maxillofacial, and general surgeons; dermatologists; glyco- and chemical biologists; and medical school students.
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